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Assessment of Renal Function in Hiv/Aids Patients on Highly Active Antiretroviral Therapy (Haart) In Abuth, Zaria

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– Assessment of Renal Function in Hiv/Aids Patients on Highly Active Antiretroviral Therapy (Haart) In Abuth, Zaria –

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Abstract

Acquired immunodeficiency syndrome (AIDS) is a spectrum of disease states characterised by progressive immunosuppression.

It results from infection with Human Immunodeficiency Virus (HIV) which is capable of affecting every organ system in the body.

Renal complications are important component of advanced HIV disease, and these complications significantly contribute to morbidity and mortality in these patients. 

Therefore, regular assessment of their renal status using sensitive markers such as Creatinine Clearance (CrCl) together with serum electrolytes, creatinine, urea and uric acid is necessary.

Introduction

Acquired Immunodeficiency Syndrome (AIDS) is a spectrum of disease states characterised by progressive immunosuppression.

It results from infection with the Human Immunodeficiency Virus (HIV) (Cotran et al, 1999; Olumide, 2003). HIV infection is a worldwide health problem that affects millions of men and women (Jeff, 2002).

Since the beginning of the pandemic in the early 1980, more than 60million people have been infected with HIV worldwide, with an estimated 25million death, and 5million new infection each year. 

Sub-saharan Africa carries the highest burden of HIV infection with an estimated prevalence of more than 80% of the world cases (AIDS epidemic update, 2002).

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