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Effect of the Ethanol Extract of Zapoteca Portoricensis Roots on Malaria-Infected Mice

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Abstract

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Introduction

Malaria remains one of the most widespread infectious diseases of our time. The latest estimates reveal that ~250 million people are infected with malaria across the globe, of whom ~800,000 die every year (WHO, 2010), the vast majority being young children.

Most available antimalarials were designed to target the pathogenic blood stages in humans and to address the constant threat of drug resistance (Fidock, 2010).

Traditional methods of treatment and control of malaria could be a promising source of potential anti-malaria drugs (Ugwu et al., 2013; Sumalata and Sreedevi, 2012; Venkat et al., 2011; Wright and Phillipson, 1990).

More than 80% of the world’s population relies on traditional medicine for their primary healthcare needs (WHO, 2008).

In developing countries, low-income people such as farmers, people of small isolated villages, and native communities use folk medicine for the treatment of common infectious diseases.

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