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Haemopoietic and Haematinic Property of the Leaf and Fruit Extract of Solanum Nigrum L (Spp Villosum) in Anaemic Albino Wistar Rats

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Abstract

Anaemia is a global public health problem affecting both developing and developed countries with major consequences for human health as well as colonial and economic development. There is paucity of data on the use and type of medicinal plants that can be used to alleviate anaemia.

Sequel to the fact that orthodox medicine can no longer give answers to our numerous different diseases in which anaemia is one of them. There is an increasing interest in the use of herbal products to supplement for these drugs.

This research is designed to investigate the haemopoeitic and haematinic properties of the aqueous leaf and fruit extract of Solanum nigrum L (spp villosum) in phenylhydrazine induced anaemic Albino Wistar Rats.

Fresh leaves and fruits of Solanum nigrum were purchased from our major and local markets in Enugu Metropolis. They were shade-dried and pulverised to fine powder. 600g each were extracted using aqueous standard method. The extracts were used to carry out this study.

Introduction

Anaemia is a global public health problem affecting both developing and developed countries with major consequences for human health as well as social and economic development (Benoist et al, 2005).

Anaemia can also be defined as a deficiency state in which there is reduced number of circulating red cells in a person’s blood or reduction in the concentration of haemoglobin in the peripheral blood below the normal range for the age and sex of the patient.

This blood disorder occurs at all stages of life, both male and female, but is more prevalent in pregnant women and young children (Benoist et al, 2005).

In 2002 Iron deficiency anaemia (IDA) was considered to be among the most important contributing factors to the global burden of the disease. Anaemia is the result of a wide variety of causes that can be isolated (Benoist et al, 2005) but more often it co-exists with other clinical conditions.

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