{"id":9345,"date":"2023-09-12T04:09:46","date_gmt":"2023-09-12T04:09:46","guid":{"rendered":"https:\/\/file.currentschoolnews.com\/?post_type=product&p=9345"},"modified":"2023-09-12T14:09:36","modified_gmt":"2023-09-12T14:09:36","slug":"assessment-of-some-biochemical-markers-of-nutritional-status-among-adult-sickle-cell-anaemia-patients-in-steady-state-in-zaria","status":"publish","type":"product","link":"https:\/\/pastexamquestions.com\/product\/assessment-of-some-biochemical-markers-of-nutritional-status-among-adult-sickle-cell-anaemia-patients-in-steady-state-in-zaria\/","title":{"rendered":"Assessment\u00a0of\u00a0Some Biochemical Markers\u00a0of\u00a0Nutritional Status Among Adult Sickle Cell\u00a0Anaemia\u00a0Patients\u00a0in\u00a0Steady State\u00a0in\u00a0Zaria"},"content":{"rendered":"

Download Assessment of Some Biochemical Markers of Nutritional Status Among Adult Sickle Cell Anaemia Patients in Steady State in Zaria<\/strong><\/span>. Medical and Health Sciences students who are writing their projects can get this material to aid their research work.<\/span><\/span><\/p>\n

Abstract<\/b><\/span><\/h2>\n

Sickle cell\u00a0anaemia\u00a0is a chronic\u00a0haemolytic\u00a0state which is characterized by\u00a0hypercatabolism\u00a0that could predispose to malnutrition.<\/span> The low socio economic\u00a0backgroundof\u00a0our patients may worsen their health status.<\/span><\/p>\n

The study was aimed\u00a0atassessing\u00a0some\u00a0biochemicalmarkers\u00a0of nutritional status among adult sickle cell\u00a0anaemia\u00a0patients in steady state in Zaria. <\/span><\/p>\n

It is a crosssectional descriptive study which was conducted in the Departments of Chemical Pathology and Haematology, Ahmadu Bello University Teaching Hospital, Shika, Zaria, Kaduna State. <\/span><\/p>\n

S<\/span>ome biochemical markers of nutritional status of 60 adult SCA patients in steady state and 60 healthy non SCA controls were assessed. <\/span><\/p>\n

Mean (\u00b1SEM) serum vitamin D concentration was significantly lower in SCA patients 14.55\u00b11.49 ug\/L compared with controls 25.87.\u00b14.29 ug\/L (p<0.05).<\/span><\/p>\n

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Introduction<\/span><\/span><\/strong><\/span><\/h2>\n

Sickle cell anemia (SCA) is a genetic disease that results from the substitution of valine for glutamic acid in the \u03b2-globin chain of the hemoglobin molecule (Pauling and <\/span>Itano<\/span>, 1949). <\/span><\/p>\n

The consequence of this amino acid substitution is the formation of hemoglobin S (<\/span>HbS<\/span>). Under low oxygen tension and\/or conditions of acidosis.\u00a0<\/span><\/p>\n

HbS<\/span>\u00a0precipitates and forms polymerized crystals called\u00a0<\/span>tactoids<\/span>\u00a0(hemoglobin polymers), which distort the red blood cells (Nelson and Cox, 2005; Ganong, 2003). <\/span><\/p>\n

T<\/span>he resulting sickle-shaped red cells lose their pliability and cannot navigate the small capillaries, become sticky, and adhere to the small veins, small arteries, and other blood vessels causing\u00a0<\/span>vaso<\/span>-occlusion (Aster, 2005; Bunn and Forget, 1977).<\/span><\/p>\n

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